dilluns 9 d'abril de 2018

DCEXS-UPF: Major milestone reached in effort to identify cancers’ genetic roots

News from DCEXS-UPF

An international team coordinated by the National Institutes of Health (NIH) have reached a major milestone in describing the genetic landscape of cancer. The researchers have completed the genetic sequencing and analyses of more than 11,000 tumours from patients, spanning 33 types of cancer. These are part of The Cancer Genome Atlas (TCGA) project, launched in 2005 to pursue the genetic basis of cancer.

Altogether, the researchers have identified about 300 genes that drive tumour growth. And, remarkably, just over half of all tumours analysed carry genetic mutations that could be targeted by therapies already approved for use in patients. The results appeared on 5 April in 27 papers published in Cell Press journals.

The researcher Li Ding at Washington University led a study group within the project and Eduardo Eyras, ICREA research professor at UPF, has participated in one of these studies published in Cell Reports.

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