L’estabulari del PRBB, de 4.500 m2, té com a missió garantir el benestar dels animals d’experimentació que es fan servir al parc, aixà com col·laborar amb els més de 130 usuaris dels diferents centres del PRBB en el disseny i realització dels assaigs. Aquests assaigs han de ser sotmesos a un procediment aprovat pel comitè ètic d’experimentació animal del PRBB, format per membres de tots els centres del PRBB i presidit per una persona externa.
L’estabulari del PRBB, el cinquè que ha ajudat a dissenyar el Dr. Juan MartĂn Caballero, director de l’estabulari, Ă©s molt competitiu a nivell mundial, i ja ha rebut les visites de delegacions de varis paĂŻsos. Recentment, representants d’universitats i companyies internacionals varen visitar l’animalari per veure l’ús que se’n fa de la robòtica per a les feines de neteja i esterilitzaciĂł. El Dr. MartĂn Caballero recorda quan va veure els primers robots al Karolinska Insitute, cap a l’any 2000, i s’enorgulleix de que el PRBB sigui ara capdavanter en aquesta tecnologia. L’estabulari del PRBB Ă©s un dels mĂ©s complexes, ja que ha d’unificar les necessitats d’investigadors que treballen en temes molt diversos, com sĂłn oncologia, immunologia, regeneraciĂł, alteracions cardio-respiratòries, enfermetats neurodegeneratives, drogoaddicciĂł i conducta, fibromialgies, i estudis de micro-PET en ratolins.
L’estabulari estĂ format per sis grans Ă reas. L’à rea d´animals aquĂ tics, supervisada pel veterinari Juan Ramos, tĂ© capacitat per a 50.000 peixos zebra, 500 granotes i 100 axolots. Per als mamĂfers hi ha una zona barrera (lliure de gèrmens patògens) capaç de mantenir 60.000 ratolins mutants, aixĂ com una Ă rea de transgènesi, ambdues supervisades per Pep Moreno, i una zona de quarantena supervisada per Mireia Juan. TambĂ© hi ha una Ă rea d’experimentaciĂł amb sales de comportament, quiròfans i irradiadors, i l’à rea de rentats i esterilitzaciĂł, coordinada per Jordi Puig, on hi actuen robots. SĂlvia GĂłmez, biòloga i gerent de l’estabulari, i Antoni Ventura, que s’assegura que l’estabulari no tanqui per vacances, acaben de conformar el personal de l’estabulari del PRBB. A finals de juliol s’incorporarĂ un tècnic encarregat d’un nou servei que oferirĂ transferències embrionĂ ries per a netejar lĂnies de ratolins que arriben de l’exterior, criopreservaciĂł, creaciĂł de transgènics i knockouts, trasplantament d’ovaris, fecundaciĂł in vitro i inseminaciĂł artificial, una tècnica aquesta encara molt difĂcil en ratolins. TambĂ© estĂ previst, a partir d’aquest juliol, l’inici de les obres d’un estabulari convencional d’uns 1.000 m2 a l’antic edifici de l’IMIM.
Taking care of the animals at PRBB.Animal facility
The aim of the animal house at the PRBB, of 4,500 m2, is to guarantee the wellbeing of the animals that are used for experimentation in the research park, and to collaborate with the more than 130 users from the different centres of the PRBB in the design and completion of the assays. These assays must be subjected to a proceeding approved by the Animal Research Ethical Committee of the PRBB, formed by members of all the centres of the PRBB and directed by an external person.
The animal facility of the PRBB, the fifth which Dr. Juan MartĂn Caballero, its director, has helped designing, is very competitive at an international level, and it has received visits from several countries. Recently, representatives from universities and companies from the US and several European countries visited it for a conference on robotics applied to animal facilities. Dr. MartĂn Caballero remembers when he saw the first robots at the Karolinska Insitute in 2000, and he’s proud that the PRBB is now a leading centre in this technology. The PRBB animal facility is also one of the most complex ones, because it has to unify the needs of researchers who work in very different subjects, such as oncology, immunology, regeneration, cardio-respiratory alterations, neurodegenerative diseases, addiction to drugs and behaviour and micro-PET studies in mice.
The animal facility comprises six independent units. The aquatic animals area, supervised by the veterinary Juan Ramos, has a capacity for 50,000 zebra fish, 500 grogs and 100 axolots. For mammals, there is a barrier zone, capable of supporting 60,000 specific pathogen germ free (SPF) mice, and a transgenesis area, both of them supervised by Pep Moreno, as well as a quarantine area supervised by Mireia Joan. There is also an experimental area, with laboratories for behaviour studies, operating rooms and an irradiator, and the robotized cleaning and sterilisation area, coordinated by Jordi Puig. SĂlvia GĂłmez, a biologist, is the manager of the animal facility, and Antoni Ventura makes sure that the facility doesn’t close during holidays. At the end of July, another technician will join the animal facility, who will offer new services: embryonic transfer to clean up the mice lines that arrive from outside, criopreservation, generation of transgenic and KO mice, ovary transplants, in vitro fecundation and artificial insemination; this last one is a technique still very difficult in mice. It is also planned that, from July 2007, the works for a conventional animal facility of about 1,000 m2 will start at the old IMIM building.
|
Ajuts i beques
Gestió de sessions
Tornar
