Clues to molecular mechanisms from the concerted action of genes

08/10/2014 12:00h.

Lugar: Sala Ramón y Cajal

Tipo evento: Sesiones científicas, CRG Group Leader Seminars

Ponentes: Robert Castelo

Organizador: Group Leader Seminars


Brief biography

Robert Castelo is associate professor at CEXS/UPF. He graduated in Computer Science by Universitat de Lleida (BSc) and Universitat Politècnica de Catalunya (MSc). After graduation, he spent 3 years at the National Research Institute for Mathematics and Computer Science (CWI) in Amsterdam, The Netherlands, investigating mathematical, statistical and computational aspects of graphical Markov models, and he got his PhD in Computer Science by the University of Utrecht. In 2002 he joined as postdoc/lecturer the UPF/CRG laboratory of Roderic Guigó working on biological sequence analysis and participating on the pilot phase of the ENCODE project. On 2006 he was awarded a "Ramon y Cajal" fellowship and started his own independent research at UPF where, on 2012, he became associate professor of Biostatistics and Bioinformatics.

The focus of his research over the last 8 years has been reverse-engineering the genotype-phenotype map from high-throughput genomics data, trying to embrace the complexity that follows from the coordinated action of genes by means of multivariate statistical models, such as graphical Markov models.